Browse: Home / Diabetes / Go on a diet even if you think you have nothing to lose

Menu

Skip to content
  • About
  • Better Body Chemistry School
  • Book a health conversation
  • Speaking query
  • The “Big” Spoons
Header image

BBC

Small things can make a big difference to your health

advertisement

Menu

Skip to content
  • Home
  • Free Resources
    • 31 days to Better Body Chemistry
    • Willpower Report
    • Weight loss e-course
    • The ups and downs of insulin resistance
    • Candy Floss Boards
    • Weight tracker
  • Library
  • Shop
  • Baobab Adventures
  • Lucky dip
  • Buy me a coffee
  • Video gallery
  • Contact

Go on a diet even if you think you have nothing to lose

Posted by Dr Sandy on in Diabetes | 178 Views | Leave a response

Calling all ‘skinny diabetics’: Prioritize weight loss to unveil metabolic wellness—discard secret fat for a healthier you. 

Watch on YouTube

Click to listen to the audio…

The science behind the fat threshold hypothesis

Fat cell dressed as a groom trying to pull his triglyceride bride over the threshold

If you are diabetic, fat or skinny, put losing weight on your agenda – getting rid of your secret fat is the key to metabolic wellness.

Type 2 diabetes is often painted as a disease of the obese, with an innuendo that well…

IT’S SOMEHOW DESERVED.

THE PERSON LET THEMSELVES GO.

The default response to the problem is a command to LOSE SOME WEIGHT.   But not all type 2 diabetics are fat so this advice can land like a wet blanket on someone who isn’t visibly “fat”.  To be honest it’s often not that helpful for someone who is visibly fat, but I digress.

Skinny diabetics

The plight of  “skinny diabetic” is often “ignored”…..

And for the record, “skinny” diabetics are pretty common – it’s estimated that 1 in 6 people diagnosed with type 2 diabetes have a BMI < 27.  These people are seldom given the “lose weight advice”, the dietary advise they’re often given is to concentrates on eliminating “offending” foods from their diet, specifically saturated fat and cholesterol. Unfortunately, when this is practiced, it can actually be counterproductive.

NOTE : Solving the metabolic problems requires “reining in insulin”, high cholesterol is usually the symptom, not the problem per se.

Time for a new perspective

This needs to change, research from Newcastle University in the UK suggests, if you’re “lean” and diabetic, losing weight should still be on your agenda.

Because “fatness” is relative.

The fat threshold hypothesis

It’s been postulated that thanks to genetics, we all have a fat threshold i.e. a maximum amount of fat we can comfortably carry.   When we exceed this threshold,  metabolic troubles manifest.

Fat deposits being depicted as fat hotels

For some the fat threshold is enormous, for others it’s tiny.

For the record, the fat cells with the problem are not actually the cells implicated in the pathology.   Belly fat is blamed, but the reason fat is accumulating in the belly, is because fat cells meant to be squirrelling away supplies for a rainy day, aren’t accepting fat deliveries.

The body resorts to plan B.

The different fat deposits on human body

Storing the fat, in other places e.g. the liver (NAFLD).

When it’s stored in the liver/pancreas, metabolic challenges follow.

Not fat enough

Now an off shoot of this idea, is that if you’re currently metabolically healthy and obese – you’re just not fat enough.  And if you continue to pack on the pounds,  it’s just a matter of time before you “break”.

This can be true, but it’s not A FACT.

Attempts to scientifically demonstrate this concept have fallen flat.

Genetically advantaged

It’s good news for some…

Obesity does not equal insulin resistance.

Having said that,  excess fat can be tough on other body parts, so carrying excess weight is not ideal,  your health is still impacted.

On the flip side, it is  bad news for some……..

BMI tells you nothing

You can be “normal” weight and be metabolically challenged i.e. a skinny diabetic.   That would be me. I had a metabolic meltdown with a BMI of just over 25.  (Normal is 18 – 25).

“Skinny fat” is the term that is euphemistically applied to this situation.

“Skinny” fat  people,  look normal weight on the outside, but inside they’re carrying extra pounds, especially pounds around the belly i.e. visceral fat.  This is captured well in this CT scan of pediatric oncology patients.

CT scan showing fat deposits in a normal weight, obese and skinny fat person

The red represents skeletal muscle, the blue subcutaneous adipose tissue and the yellow visceral adipose tissue. The person in the middle is skinny fat. You can see the blue layer is relatively thin i.e. close to normal, but there is lots of yellow inside the body. It’s the yellow bits that are the problem in someone who is “skinny” fat.

Unfortunately falling into the category of “skinny” fat often puts you on a worse health trajectory, than someone who is genuinely fat.

The curse of the “skinny” fat

One of the reasons…………

You’re often flying under the radar.

Unlike in the obviously “FAT”, the medical fraternity is NOT expecting trouble, so they don’t  always pick up problems and the seldom advise weight loss.

NOTE :  Should trouble be found, prescription meds are the GO TO SOLUTION.  the thinking is there is NOTHING you can do to FIX the situation.

The counterintuitive solution

Actually there is something you can do.

LOSE SOME of your “secret” fat.

Fat cells leaving a skinny fat doll

It has the potential to make a difference to your metabolic health.

Fat thresholds are REAL.

The reTUNE study

This is what happened to a group of  skinny diabetics,  when they participated in the reTUNE  (Reversal T2DM upon normalization of energy intake) study, between May 2018 and Nov 2021.

Here is a little background about these peeps.  There were 20 in total, they all had a diagnosis of type 2 diabetes, their diabetes was being managed with diet/drugs, not insulin.   None of them had been diabetic for an extensive period of time (all were less than 6 years into their diabetic experience). Genetic tests confirmed that none of them were suffering from monogenic or autoimmune diabetes.   

NOTE : This is important to know, dieting will NOT fix all people with a diagnosis of type 2 diabetes. 

The “skinny” diabetics

They were normal weight – you are only considered to be overweight if you have a BMI > 25.  But they did have expanded bellies (you can see this in their waist circumference) and their blood work showed dyslipidemia.  The values in read are considered normal. The one’s to watch are triglycerides and HDL.  LDL cholesterol although often higher in someone with metabolic syndrome it is not a marker of insulin resistance.

Table showing weight and lipid profiles at start of study and at the end of weight loss protocol

Two cycles of “dieting” helped them lose their “bellies” and corrected the lipid profile, an effect which was still seen a year later.

“Curing” type 2 diabetes

But this study is about REVERSING diabetes…..so the most interesting numbers are these ones.  Both HbA1c and fasting blood glucose had dropped back down to normal.  OMG !   The skinny diabetics were “cured”.

HbA1c and fasting sugar levels after the weight loss protocol

Time course of change in glycemic measures after each cycle of weight loss and at 12 months © 2023 Roy Taylor et al.

I know what you want to know NOW.

What diet did they follow ? 

They pretty much “starved”.  For a period of 2-4 weeks, they followed a low calorie diet, consuming a meal replacement formula which provided them with  600 kCal a day.  To put this in perspective, we typically eat 2000 – 2500 kCal a day, so 600 kCal a day is running on fumes. Lol !

This was followed by 4-6 weeks of “normal” eating, the diet that was recommended was a Mediterranean style eating pattern.

Just two torture sessions

For one person, one round of this “torture” was enough to move the needle and get them back to “normal”.

Most needed two sessions.

Fun cartoon showing how a lady participating in the study would feel following the protocol

A few opted/needed three to reverse their skinny diabetes.

This study suggests fat thresholds DO EXIST.

And if you lucked out on the genetic lottery, lightening the load, by losing some of your SECRET fat, can make a difference to your metabolic health.  Yah !

Carpe Diem (SEIZE THE DAY)

A week or two of severely cutting your calorie intake is probably something we all can do. If you need a little help “starving”, try this technique Chinese monks use to help them fast for religious occasions.

The important thing, SHORT AND SHARP.

Don’t drag it out.

Dragging your calorie restriction out over an extended period of time, can back fire, because your body is likely to make adjustments to your basal metabolic rate, which will see you fighting to keep the weight off.  Click here to learn more.

The take home message from this research….

“Dieting” is for everyone

Thin or fat, if you’re dancing on the edge of being diabetic, GO ON DIET for  a week or two even if you think you have nothing to lose.   You might just gain back your metabolic health.

And this is priceless.

NOTE : Being insulin resistant puts you at an increased risk of EVERYTHING.

Slow and steady wins the day

If the idea of “starving” for 2 weeks puts you into a panic, you can achieve the same result with the slow and steady approach of CANDY FLOSSing.  The extra fat might not fly off quite as fast, but little by little it will move out and you’ll develop a sustainable lifestyle that will keep the weight off, FOREVER.

Download the Willpower Report, it’s free and begin the journey today to creating BETTER BODY CHEMISTRY and BETTER HEALTH. BETTER BODY CHEMISTRY.

Aetiology of Type 2 diabetes in people with a ‘normal’ body mass index: testing the personal fat threshold hypothesis. Clinical Science (2023) 137 1333–1346. Roy Taylor , Alison C. Barnes, Kieren G. Hollingsworth et al

Prediction of whole body composition utilizing cross-sectional abdominal imaging in paediatrics. Eur J Clin Nutr (2023) 77(6):684-691. Rebecca Deyell, Sunil Desai, Andrea Gallivan, Alecia Lim, Michael Sawyer, Steven Heymsfield, Wei Shen, Vicky Baracos. 

Further reading

GABA keeping a beta cell awake

Is this the secret to fixing the hyperinsulinemia ? 

Fat filled liver cells leak GABA, which hooks up with GABA receptors on the hepatic afferent nerve, to slow nerve firing and this increases insulin secretion

more fat cells

To be healthy, you need MORE fat cells, not less 

You can be fat, with lots of fat cells (hyperplasia) or you can be fat with fewer fat cells (hypoplasia). More fat cells is better from a health perspective

macrophage infiltration of adipose

Fat cells NEED a little inflammation to grow BIG and STRONG

When you get BIGGER, you go on a shopping spree (hopefully) to get bigger clothes, bigger fat cells need more space too……… inflammation drives this process

 

Want to discover more ways to create BETTER BODY CHEMISTRY ?

Posted in Diabetes | Tagged belly fat, body composition, fasting, fat threshold, fatty liver, fatty pancreas, obese, reversing diabetes, skinny, skinny diabetic, type 2 diabetes

Sugar gremlins are REAL

Watch on YouTube

Instagram

betterbodychemistry
@betterbodychemistry
Follow
LOW cholesterol isn’t automatically safe.

That’s the curveball.

We focus so hard on lowering LDL…
we forget it’s doing a job.

And midlife is when these conversations start showing up —
cholesterol, statins, shifting risk.

If this is on your radar…
there’s a free Navigating the Middle Years bundle open right now.

50+ resources on midlife health, hormones and what’s actually going on.

⏳ Closes tomorrow

Hop inside, you'll find the link in bio.

#midlifehealth #menopausehealth #womenshealthover40
#cholesterol #statins #ldl #hearthealth
#metabolichealth #biologymatters
betterbodychemistry
betterbodychemistry
•
Follow
LOW cholesterol isn’t automatically safe. That’s the curveball. We focus so hard on lowering LDL… we forget it’s doing a job. And midlife is when these conversations start showing up — cholesterol, statins, shifting risk. If this is on your radar… there’s a free Navigating the Middle Years bundle open right now. 50+ resources on midlife health, hormones and what’s actually going on. ⏳ Closes tomorrow Hop inside, you'll find the link in bio. #midlifehealth #menopausehealth #womenshealthover40 #cholesterol #statins #ldl #hearthealth #metabolichealth #biologymatters
4 weeks ago
View on Instagram |
1/9
You know that phase where things just feel a bit… off? 👀 Like what used to work for your body and health just doesn’t anymore, but you’re not totally sure what to do about it? Yeah. That one.

I am so excited to announce that my workshop, Cholesterol Curveball: What Women Need to Know, is officially part of the Navigating The Middle Years Bundle! If you've been feeling confused or overwhelmed by your changing cholesterol numbers during midlife, I created this specifically to give you practical, no-fluff answers.

Even better, I’ve teamed up with a group of amazing creators to include my workshop alongside 50+ other resources designed exactly for this stage of life. The bundle covers: ✨ energy + health (including my cholesterol workshop!) ✨ confidence + boundaries ✨ “what now?” clarity ✨ practical next steps

🎁 It’s completely free (for a limited time).

Head to the link in my bio to grab your free copy before it's gone!

#CholesterolManagement
#WomensHeartHealth
#HighCholesterol
#MenopauseHealth
#PerimenopauseHealth
#MidlifeWomen
#NavigatingMidlife
#WellnessJourney
betterbodychemistry
betterbodychemistry
•
Follow
You know that phase where things just feel a bit… off? 👀 Like what used to work for your body and health just doesn’t anymore, but you’re not totally sure what to do about it? Yeah. That one. I am so excited to announce that my workshop, Cholesterol Curveball: What Women Need to Know, is officially part of the Navigating The Middle Years Bundle! If you've been feeling confused or overwhelmed by your changing cholesterol numbers during midlife, I created this specifically to give you practical, no-fluff answers. Even better, I’ve teamed up with a group of amazing creators to include my workshop alongside 50+ other resources designed exactly for this stage of life. The bundle covers: ✨ energy + health (including my cholesterol workshop!) ✨ confidence + boundaries ✨ “what now?” clarity ✨ practical next steps 🎁 It’s completely free (for a limited time). Head to the link in my bio to grab your free copy before it's gone! #CholesterolManagement #WomensHeartHealth #HighCholesterol #MenopauseHealth #PerimenopauseHealth #MidlifeWomen #NavigatingMidlife #WellnessJourney
1 month ago
View on Instagram |
2/9
There is still time to catch my session and tune into all the other amazing presentations happening inside the Bloom & Be Summit. 

Its a free virtual Self-Care Experience for anyone who wants growth, joy, and intentional living…but doesn’t resonate with hustle culture or rigid routines. 

This experience is about small, meaningful shifts that expand your capacity…not overwhelm it.

NOTE : You don’t have to watch everything. You don’t have to change everything. You’re allowed to move gently.

If you’re ready for self-care that meets you where you are, Bloom + Be might be exactly what you need.

Join us March 24–26 (🔗in-bio)

#BloomAndBeSummit #SweetDreams #NightRoutine #BedtimeRitual #SelfCareSummit #RestfulSleep #GentleLiving #FireflyKisses #WindDown #DeepSleep
betterbodychemistry
betterbodychemistry
•
Follow
There is still time to catch my session and tune into all the other amazing presentations happening inside the Bloom & Be Summit. Its a free virtual Self-Care Experience for anyone who wants growth, joy, and intentional living…but doesn’t resonate with hustle culture or rigid routines. This experience is about small, meaningful shifts that expand your capacity…not overwhelm it. NOTE : You don’t have to watch everything. You don’t have to change everything. You’re allowed to move gently. If you’re ready for self-care that meets you where you are, Bloom + Be might be exactly what you need. Join us March 24–26 (🔗in-bio) #BloomAndBeSummit #SweetDreams #NightRoutine #BedtimeRitual #SelfCareSummit #RestfulSleep #GentleLiving #FireflyKisses #WindDown #DeepSleep
1 month ago
View on Instagram |
3/9
If you’ve been craving self-care that actually supports your real life…this is for you.

Bloom + Be: A Gentle Self-Care Experience is a free, 3-day virtual self-care event happening March 24-26, created for creative, kindhearted women who want more joy, clarity, and momentum…without hustle culture or pressure.

This isn’t about adding more to your to-do list.

It’s about caring for your mind, body, and energy in ways that help you feel lighter and more connected to yourself.

Come exactly as you are. Take what helps. Leave the rest.

Free tickets are available now (🔗in-bio)

#BloomAndBe
#BloomAndBeSummit
#SleepBetter
#FallAsleepFast
#SleepScience
#MindBodySoul
#SlowLiving
#NourishYourself
#HolisticWellness
betterbodychemistry
betterbodychemistry
•
Follow
If you’ve been craving self-care that actually supports your real life…this is for you. Bloom + Be: A Gentle Self-Care Experience is a free, 3-day virtual self-care event happening March 24-26, created for creative, kindhearted women who want more joy, clarity, and momentum…without hustle culture or pressure. This isn’t about adding more to your to-do list. It’s about caring for your mind, body, and energy in ways that help you feel lighter and more connected to yourself. Come exactly as you are. Take what helps. Leave the rest. Free tickets are available now (🔗in-bio) #BloomAndBe #BloomAndBeSummit #SleepBetter #FallAsleepFast #SleepScience #MindBodySoul #SlowLiving #NourishYourself #HolisticWellness
1 month ago
View on Instagram |
4/9
Everyone fears sugar spikes… but almost no one realises sugar crashes shake your blood vessels too.
Inside your bloodstream, stability matters more than perfection.

Agent Vaso is the quiet operator keeping your flow steady — until things drop faster than he can respond.

If you want more molecule-level stories that help you understand what’s actually happening in your body, follow along.

This is the biology no one ever teaches you.

#sugarcrash
#hypoglycemia
#bloodflow
#endothelium
#vascularhealth
#bloodvessels
#healthyflow
#glucoselevels
#glycemicvariability
#betterbodychemistry

#betterbodychemisty
betterbodychemistry
betterbodychemistry
•
Follow
Everyone fears sugar spikes… but almost no one realises sugar crashes shake your blood vessels too. Inside your bloodstream, stability matters more than perfection. Agent Vaso is the quiet operator keeping your flow steady — until things drop faster than he can respond. If you want more molecule-level stories that help you understand what’s actually happening in your body, follow along. This is the biology no one ever teaches you. #sugarcrash #hypoglycemia #bloodflow #endothelium #vascularhealth #bloodvessels #healthyflow #glucoselevels #glycemicvariability #betterbodychemistry #betterbodychemisty
2 months ago
View on Instagram |
5/9
If you enjoy understanding your chemistry instead of guessing, come hang out in my world.

👉 Follow @betterbodychemistry
👉 Join my weekly email list - you will find the link in my bio

#nocturia #nighttimepee #sleephealth #hearthealth #fluidretention #metabolichealth #insulinresistance #betterbodychemistry #scienceexplained #healthscience #overactivebladder #sleepbetter #agingwell
betterbodychemistry
betterbodychemistry
•
Follow
If you enjoy understanding your chemistry instead of guessing, come hang out in my world. 👉 Follow @betterbodychemistry 👉 Join my weekly email list - you will find the link in my bio #nocturia #nighttimepee #sleephealth #hearthealth #fluidretention #metabolichealth #insulinresistance #betterbodychemistry #scienceexplained #healthscience #overactivebladder #sleepbetter #agingwell
3 months ago
View on Instagram |
6/9
I’ve spent a long time trying to figure out how to explain what I actually do in a way that feels honest — not salesy, not dramatic, and not simplified to the point of being wrong.

What I finally landed on is something I call Unlocking Better Body Chemistry.

It’s not a program or a protocol.
It’s a way of looking at health problems — especially metabolic ones — that focuses on why things aren’t responding, instead of just chasing symptoms.

Most people I talk to are already doing a lot of “right” things.
They’re just doing them without a clear understanding of how their own body is functioning.

This framework is how I make sense of bloodwork, symptoms, and context together — and how I help people stop guessing about what actually matters.

I’ve put it all into a page so it’s clear, grounded, and easy to read.

If you’re curious, you can read it here. (link in first comment)

#signatureframework #metabolichealth #healthframework #healthwithoutthehype
betterbodychemistry
betterbodychemistry
•
Follow
I’ve spent a long time trying to figure out how to explain what I actually do in a way that feels honest — not salesy, not dramatic, and not simplified to the point of being wrong. What I finally landed on is something I call Unlocking Better Body Chemistry. It’s not a program or a protocol. It’s a way of looking at health problems — especially metabolic ones — that focuses on why things aren’t responding, instead of just chasing symptoms. Most people I talk to are already doing a lot of “right” things. They’re just doing them without a clear understanding of how their own body is functioning. This framework is how I make sense of bloodwork, symptoms, and context together — and how I help people stop guessing about what actually matters. I’ve put it all into a page so it’s clear, grounded, and easy to read. If you’re curious, you can read it here. (link in first comment) #signatureframework #metabolichealth #healthframework #healthwithoutthehype
3 months ago
View on Instagram |
7/9
If your liver folded watching this — you’re exactly who I talk to every week.

Not your standard eat less and move more advice.
Not wellness fluff.
Biochemistry.

Join the Better Body Chemistry list.
📩 Link in bio.

#fattyliver
#insulinresistance
#metabolichealth
#alcoholandhealth
#metabolicstress
#insulinresistant
#metabolichealthtips
#NAFLD
#betterbodychemistry
betterbodychemistry
betterbodychemistry
•
Follow
If your liver folded watching this — you’re exactly who I talk to every week. Not your standard eat less and move more advice. Not wellness fluff. Biochemistry. Join the Better Body Chemistry list. 📩 Link in bio. #fattyliver #insulinresistance #metabolichealth #alcoholandhealth #metabolicstress #insulinresistant #metabolichealthtips #NAFLD #betterbodychemistry
3 months ago
View on Instagram |
8/9
Your body isn’t misbehaving.
Its clocks are out of sync.

Every cell runs a molecular timekeeper — CLOCK, BMAL, PER and CRY — driving your energy, appetite, sleep pressure and mood.

When those clocks drift, everything feels “off,” and people blame willpower instead of timing.
If you want science that explains your biology (not wellness slogans), link in bio to join my email list

#circadianrhythm #molecularclock #CLOCK #BMAL #PER #CRY #circadianbiology #bodyclock #metabolism #timing #BetterBodyChemistry
betterbodychemistry
betterbodychemistry
•
Follow
Your body isn’t misbehaving. Its clocks are out of sync. Every cell runs a molecular timekeeper — CLOCK, BMAL, PER and CRY — driving your energy, appetite, sleep pressure and mood. When those clocks drift, everything feels “off,” and people blame willpower instead of timing. If you want science that explains your biology (not wellness slogans), link in bio to join my email list #circadianrhythm #molecularclock #CLOCK #BMAL #PER #CRY #circadianbiology #bodyclock #metabolism #timing #BetterBodyChemistry
3 months ago
View on Instagram |
9/9
View on Instagram
  • Popular
  • Featured
  • Recent
  • asprosin the sugar plum fairy

    Why sugar levels are high despite NOT eating

    23075 views / Posted
  • oatmeal breakfast being beaten by egg

    Which is a better breakfast, egg or oatmeal ?

    22820 views / Posted
  • poop getting stuck

    The fix for constipation is to go on a low fibre diet

    22512 views / Posted
  • chewing gum relieving postoperative ileus

    A stick of chewing gum gets the gut going after surgery

    17006 views / Posted
  • carbonated water bubbles fill you up

    Fizzing up the water flattens your appetite

    15880 views / Posted
  • sun extracting cholesterol

    Make sure you have your “annual” check-up in the summer time

    / Dr Sandy
  • sending your kid to bootcamp won't stop childhood obesity

    Moving more won’t stop your kid from getting fat

    / Dr Sandy
  • cholesterol at the scene of the accident

    Bone cells are stiffening up your arteries not cholesterol

    / Dr Sandy
  • brain size the problem in ADHD

    Are kids with ADHD just acting according to their brain age

    / Dr Sandy
  • plastering the blood vessel with calcium

    Calcium supplements are building bones and breaking hearts

    / Dr Sandy
  • Plant baring hamburgers

    Does Soy Build Muscle? Exploring the Science Behind Protein Choices

    / Dr Sandy
  • img-42

    The Dark Side of Weight Loss Drugs

    / Dr Sandy
  • Mother Nature stealing from peter to pay paul

    Are You Losing Muscle Without Realizing It? Here’s How to Protect It

    / Dr Sandy
  • img-44

    Your Resting Heart Rate could be a Red Flag for Metabolic Trouble

    / Dr Sandy
  • baby muscle mesmerized by the TV

    Tots watching too much TV end up being muscle flops

    / Dr Sandy

RSS Recent posts

 
 
 

Categories

Featured posts

  • asprosin the sugar plum fairy

    Why sugar levels are high despite NOT eating

    23075 views / Posted
  • oatmeal breakfast being beaten by egg

    Which is a better breakfast, egg or oatmeal ?

    22820 views / Posted
  • poop getting stuck

    The fix for constipation is to go on a low fibre diet

    22512 views / Posted
 

©2011-2025 Spoonful of Science

Menu

  • Meet Dr Sandy
  • Disclosure/disclaimer
  • Privacy policy
  • Comment policy
  • Contact