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How caffeine works to get you going and going

Posted by Dr Sandy on in caffeine | 692 Views | 2 Responses
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How caffeine works to keep you going and going

caffeine works through a little deception

The accumulation of adenosine tells your brain it is time for a nap. Caffeine stops the adenosine message so your brain doesn’t realize you’re really tired.

Officially caffeine acts as an antagonist at the adenosine receptors – particularly A2 receptor.

Unless you’re into pharmacology, antagonist at the adenosine receptor means nothing – so let me try to explain how caffeine works, in more familiar terms.

ATP the currency of the body

Money makes the world go round. The substance that makes your body “go round” is called ATP (adenosine triphosphate). Your body takes the food you eat and turns it into ATP, in a process known as respiration (respiration is not breathing / gaseous exchange it is a chemical reaction which creates ATP). ATP is the “currency” used to “pay” for all the transactions (reactions) in your body.

The ATP molecule is a big spender

ATP releases energy in a complex chemical reaction.

AATPTP to  ADP + Pi +  ENERGY

This energy drives all the reactions in your body from muscle contractions to moving molecules from one place to the other etc.

From riches to ragsadenosine

Unfortunately Mr Money Bags doesn’t save for a rainy day, so when the energy has been consumed, he is left penniless in the form of a substance known as adenosine.

If any of you have been in this financial predicament, then you will know how demoralizing this is. You really aren’t able to go out on the town, so the best thing to do is to head for “bed”.

A day in the life

This is what happens in your body. You start the day (hopefully) full of energy, but as the day wears on, and you do all the things you need to do, that energy is used up. Eventually there isn’t too much energy left and your body is full of adenosine.

adenosine going to bedThe penniless adenosine then goes to his “bed”. The “bed” is an adenosine receptor, a special molecule located on membranes throughout your brain. Once adenosine hops on the receptor/bed this signals your body that you should do the same.

The more adenosine molecules being created and calling it quits for the day, the more tired you’re body feels, as your energy levels drop off.

Certainly your get up and go has got up and went. Your sunny disposition has also left the building so you become increasingly grouchy and aggressive. You become a bit of a cluts and lose the “Yes we can” attitude.

Time to catch a few Zeeeeees

The superwise use this signal to have a snooze.

However, unfortunately your boss / teacher or other slave driver, may not be willing for you to take the much needed rest.

So you reach for your caffeine fix

The caffeine fix may be in the form of coffee, cola or an energy drink.

The caffeine works, by tricking the adenosine signalling system. Caffeine  hops on the bed and starts bouncing away, preventing the adenosine molecule from binding and going to sleep.caffeine taking out adenosine

Caffeine works through deception

The end result your body is deceived into thinking that you still have lots of energy available, so you can go, go, go. It takes approx 10 minutes to begin to feel a little perky and the effect will usually last 4 – 6 hours.

Of course, you are still in sleep debt.

You will have to pay the price, sooner or later.  So you do need to use caffeine wisely. Click here, to discover how to create BETTER BODY CHEMISTRY with caffeine.

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Caffeine and adenosine. J Alzheimers Dis (2010) 20 Suppl 1:S3-15. Ribeiro JA, Sebastiao, AM.

Further reading

bees addicted to caffeine

Caffeine increases bee productivity

Turns out humans are not the only ones enjoying the brain boosting, mood lifting powers of the caffeine molecule. Bees appear to also enjoy the benefits of a sip or two of caffeine.

caffeine controlling SHBG

A coffee a day keeps diabetes away

Despite the fact that a cup of joe, drop kicks a little glucose into the system it protects from diabetes. Scientists think they know why ……. hormones.

nootropic medicine cabinet

What can I take to boost brain performance ?

Caffeine is just one of the many options avaiable to improve performance. Cognitive enhancers come in many shapes and sizes.

 

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Posted in caffeine | Tagged adenosine, adenosine antagonist, ATP, caffeine, coffee, cola, energy drink

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