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Could your fat cells be turning you into half a man ?

Posted by Dr Sandy on in Obesity | 4178 Views | Leave a response
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Busy fat cells “neutralize” the testosterone squeeze by painting testosterone pink – this STEALS your manhood. Don’t let it happen to you. 

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How to use biology to fight low T

fat cell spraying testosterone pink

Busy fat cells “neutralize” the testosterone squeeze by painting testosterone pink – this STEALS your manhood. Don’t let it happen to you.

Every man’s goal…………. is to be THE ALPHA MALE and get the girl.

It’s an objective, which is hard wired into the male brain.  Granted, some men are born with a genetic “advantage”, allowing them to rule many castles, but healthy doses of testosterone, ensure every man is at least king of his own castle.

But biology conspires against castle domination.

It’s called GETTING OLD.

It’s happens to EVERYONE.

But, old age is not the only threat to castle domination – unfortunately,  having a big belly, accelerates the biology.

Not just bellyaching fat cells 

Now when you are insulin resistant, the big belly is a tumultuous mix of unhappy fat cells and trigger happy macrophages.  Unhappy fat cells typically do not suffer in silence, they protest loudly, spitting out a slew of chemicals.

It is this chemical blend that contributes to insulin resistance and associated health troubles.

But you don’t have to be insulin resistant for testosterone to take early retirement….

All it takes, is lots of fat cells.

Fats on the move

Fat cells are not just storage cupboards, they are continuously moving  fat about, to feed hungry cells.  Now whether they are in a giving or a receiving mood, depends on hormonal cues.

Testosterone is one of the hormones they are subject to.

Since testosterone is all about BUILDING MUSCLE and things,  he works hard to ensure “his boys” are taken care of.  He does this by  strong arming fat cells to mobilize fat supplies…..

a fat cell being bullied by testosteroneTestosterone puts the squeeze on

To get the necessary resources,  he cuts off their fat supplies, by inhibiting  their lipoprotein lipase enzyme. Lipoprotein lipase, is  the enzyme fat cells depend on, to off load the fat particles that have been sent their way.

With LPL PUT OUT OF COMMISSION, the fats are diverted elsewhere.

Now, this is not the only way testosterone fuels his GROWTH PLAN.  He also arranges for the catecholamine system, to  light a fire under the fat cells, so they release MORE  fuel.

Testosterone banished from the castle

So testosterone makes you a lean mean fighting machine….

But he is HARD on fat cells.

Busy fat cells sometime need to take a break – so they fight back.  Built into the fat cell’s milieu, is an enzyme or two,  that “neutralizes” the testosterone squeeze.

Revenge of the fat cells

The first way fat cells can put a stop to the continuous bullying by testosterone is to lull him into a coma of sorts – this inactivates him.  The enzyme that ultimately  removes testosterone from the picture is keto reductase 1c enzyme – AKRIc for short.

a fat cell playing a flute mesmerizing mr T

The whole thing is quite innocent.

But, the second enzyme, in the fat cell arsenal is aromatase –this enzyme  is far more malicious.  It does not just inactivate him, it feminizes him –  turning him into the girl hormone, estrogen.

 So our hot blooded male ends up swimming with the girlie hormone, estrogen.

Now every man does have a little estrogen circulating, because there are some jobs that only a girl can do.   But, the operative word, is A LITTLE.

Painting testosterone pink

When fat cells fight dirty and turn testosterone into estrogen, the estrogen levels begin to rise.  This  upsets gonoadotropin releasing  hormone, as she preens in front of her magic mirror.

Gonadotropin hormone angry at the presence of estrogen

The increased levels of estrogen make her hopping mad.

Annoyed at the presence of ANOTHER WOMEN, she puts a stop to testosterone production.

Testosterone becomes an endangered species

how fat cells sabotage fat burningA very unfortunate situation develops….

  • Less testosterone is pumped into the system – since testosterone is an anabolic hormone, the demand for fuel is lower.
  • But when the body is not actually burning fat, it needs more cupboards to store it. More fat cells are born, the process is known as adipogenesis.
  • More fat cells mean……. more aromatase, which means more estrogen, causing more confusion in the brain.
  • And……….. less testosterone aka low T / testosterone deficiency.

In extreme cases – man boobs and infertility, aka half a man syndrome, a situation that is officially described as hypogonadism.

Testosterone deficiency an inside job

Fortunately, t for most regular overweight Jo’s, this testosterone deficiency does not show on the outside, but it shows on the inside, it contributes to disease.

Testosterone is an atheroprotective chemical, this means it protects from heart disease.

When it goes awol, the risk of a heart attack or stroke, increases…..

It’s a vicious cycle

Less testosterone makes you fat and being fat leaves you with less testosterone.

To create BETTER BODY CHEMISTRY,  want to BOOST your  testosterone levels !

Testosterone in a bottle

But, don’t make the mistake of thinking testosterone in a bottle will save you.  It won’t….

Those pesky fat cells will do the same thing to this testosterone.

GnRH ordering the shut down of testosterone production

And, the hormone queen, gonadotrophin releasing hormone, will feel………… threatened and shut down the testosterone production machine.

So you need to be go after the problem….

Decrease the number of fat cells

If you’ve got rolls of fat – do what you can to lose some of it.

I know this is often easier SAID than done.  I have a free e-course that will give you some pointers.

enrol is zero to one course
It’s easy to consume and gives you the option to dig deeper into the science, should you want to. Click on the image to access it.

Be a mans kind of man

And encourage your body to make more testosterone by being MANNLY.

  • Eat like a man – eat steak, not salad. Testosterone is made from cholesterol.
  • Work out – do a little power lifting and do it aggressively
  • Be a real jock do it for 8 hours.

NOTE : If you feel this is more than you can handle, explore the option of using an aromatase inhibitor. This is a drug that blocks the ability of fat cells to feminize testosterone.  Unfortunately, it blocks the enzyme in other places too – the downside of drugs, they give and take.   But, in this case, the give is more aligned to “fixing” the broken body chemistry, than taking a testosterone supplement.

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The Role of Androgen in the Adipose Tissue of Males. World J Mens Health (2013) 31(2): 136-140. Hyun-Ki Lee, Joo Kyung Lee, Belong Cho.

Male Obesity-related Secondary Hypogonadism – Pathophysiology, Clinical Implications and Management. Eur Endocrinol  (2019) 15(2):83-90. Cornelius J Fernandez  , Elias C Chacko  , Joseph M Pappachan 

Further reading

 

sleep deprivation knocks testosterone levels

Real jocks do it for 8 hours a night

Too little sleep can turn you into a sorry looking wimp with zero get up an go, because sleep deprivation causes testosterone levels to plummet

hormones riding cow

You’re getting a little or hell of a lot of estrogen with that hamburger

Instead of that beef burger, you choose a tofu burger. Did you know, that tofu burger has more estrogen in it, than a hormone replacement pill ?

phytoestrogens taking out sperm

Soy foods shooting down the little guys 

We’ve been programmed to believe soy is a health food, but as far sperm are concerned, the lady of the soy bean wreaks havoc on sperm counts.

 

Want to discover more ways to create BETTER BODY CHEMISTRY ?

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Posted in Obesity | Tagged alpha male, aromatase, atherosclerosis, big belly, estrogen, fat cells, heart disease, infertility, Testosterone

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Dr Sandy Dr Sandy Evans, PhD

Located in Johannesburg, South Africa

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Disclaimer : The stories and articles are provided as a service. Dr Sandy's opinions are for information only, and are not intended to diagnose or prescribe. For your specific diagnosis and treatment, consult your doctor or health care provider.
 
 

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